Evaluation of Intraoperative and early postoperative Growth Hormone Levels for Transsphenoidal Resection in Acromegaly

Completed

• Conditions: acromegaly; growth hormone producing pituitary adenoma; 10021112; 10029209; 10009720

• Registration Number: NL-OMON41147
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

Patients with acromegaly and selected for elective transsphenoidal resection pituitary adenoma in the AMC.

Exclusion Criteria

All patients that are selected for elective transsphenoidal pituitary adenoma resection for acromegaly are included. When, after being informed about the research protocol, patients do not wish to participate they will not be included.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The acquired growth hormone levels will be compared with the outcome of the<br /><br>OGTT (which is plannend according to current protocol) in order to determine<br /><br>curation. Subsequently the predictive value of peroperative growth hormone<br /><br>levels for curation of acromegaly can be determined. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>none</p><br>