Pre- and postoperative evaluation of patient-parameters to investigate the outcome after endothelial keratoplasty

Recruiting

• Conditions: H18.5; H18.1; Hereditary corneal dystrophies; Bullous keratopathy

• Registration Number: DRKS00007566
• Lead Sponsor: Augenklinik Universität Düsseldorf

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2014-12-02
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 5000

Inclusion Criteria

Ability to give informt consent, informt consent to participate in the trial, indication for lamellar keratoplasty

Exclusion Criteria

contraindications for endothelial keratoplasty, unability to participate at the follow-up investigations.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Functional result (visual acuity testing, Snellen chart), transplant survival (slit lamp investigation). <br>The investigations are performed preoperatively, and 6 weeks, 4-6 months, and 12 months postoperatively, followed by annual investigations in a 10 year follow up.

Secondary Outcome Measures

Name	Time	Method
Quality of vision (color vision, visual field testing), corneal status (endothelial cell density, corneal thickness, optical coherence tomography), intraocular pressure (standardised measurement by Goldmann applanation tonometry), development/progression of ocular comorbidities (fundus control, dry eye evaluation, corneal sensitivity measurement).<br>The investigations are performed preoperatively, and 6 weeks, 4-6 months, and 12 months postoperatively, followed by annual investigations in a 10 year follow up.