Effect of Hyperbaric Oxygen Therapy on Patients With Sudden Sensorineural Hearing Loss and Coagulation Function
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 1,309
- Locations
- 1
- Primary Endpoint
- Hearing recovery rate
Study Overview
Brief Summary
The objective of this observational study was to understand the effect of HBO on patients with SSNHL and its association with coagulation function and prognosis.
The main question it aims to answer is whether HBO therapy can improve outcomes and coagulation function in patients with SSNHL.
The prognosis of SSNHL patients receiving HBO and SSNHL patients not receiving HBO were compared
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 18 Years to 75 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Meet the diagnostic criteria for sudden deafness in the American Academy of Otolaryngology Head and Neck Surgery 2019 Clinical Practice Guidelines for Sudden Deafness;
- •Aged 18-75 years old;
- •Patients with unilateral sudden deafness for the first time, and the onset time is less than 2 weeks.
Exclusion Criteria
- •Patients with other ear diseases, such as auditory trauma, barotrauma, retrocochlear disease, bilateral hearing loss, history of chronic otitis media in the same ear, and history of surgery in the same ear;
- •Patients with serious primary diseases such as heart, liver, kidney dysfunction and hematopoietic system diseases;
- •Pregnant and nursing patients;
- •Accompanied by serious mental illness;
- •Patients with incomplete clinical data.
Outcomes
Primary Outcomes
Hearing recovery rate
Time Frame: From onset to 3 months after treatment
The rate of hearing recovery in patients with all levels of hearing loss at completion of treatment and at 3 months after termination of treatment was assessed according to the WHO Hearing Loss Rating Criteria 2021 to determine the success of treatment.
Secondary Outcomes
No secondary outcomes reported
Investigators
Sun Yuting
PhD student
Shanghai University of Traditional Chinese Medicine