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Clinical Trials/EUCTR2008-001972-55-NL
EUCTR2008-001972-55-NL
Active, not recruiting
Phase 1

Efficacy of hyperbaric oxygen therapy in the treatment of late radiation damage, osteoradionecrosis, of the lower jaw. - Efficacy of hyperbaric oxygen therapy in the treatment of osteoradionecrosis of the jaw

MC St Radboud0 sites128 target enrollmentJune 11, 2008

Overview

Phase
Phase 1
Intervention
Not specified
Conditions
Osteoradionecrosis of the jaw due to previous radiotherapy treatment in the head and neck region
Sponsor
MC St Radboud
Enrollment
128
Status
Active, not recruiting
Last Updated
4 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
June 11, 2008
End Date
TBD
Last Updated
4 years ago
Study Type
Interventional clinical trial of medicinal product
Sex
All

Investigators

Sponsor
MC St Radboud

Eligibility Criteria

Inclusion Criteria

  • Informed consent
  • age \>18yrs
  • WHO performance status 0\-2
  • Last radiotherapy treatment 6 months or more ago.
  • Radiotherapy with curative intent \> 55Gy. Osteoradionecrosis in primary radiotherapy field.
  • No signs of local recurrence or primary tumour
  • Necrosis of the jaw and / or bone exposition of at least 1 cm, non\-healing extraction wound, dehiscence of the alveolar proces or linea mylohyoidea.
  • Are the trial subjects under 18? no
  • Number of subjects for this age range:
  • F.1\.2 Adults (18\-64 years) yes

Exclusion Criteria

  • Hyperbaric oxygen treatment in medical history
  • Bisphosphonate treatment in medical history
  • Re\-radiation
  • Osteosynthesis material in the affected area
  • Distant metastases
  • Local recurrence or primary tumour
  • Synchronous preventive treatment (extraction

Outcomes

Primary Outcomes

Not specified

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