The effectiveness of hyperbaric oxygen therapy on pure tone audiogram outcome of patients with sudden sensorineural hearing loss. A prospective, randomized, interventional, controlled clinical trial.

Medical School of Aristotle University of Thessaloniki0 个研究点目标入组 50 人开始时间: 2016年9月29日最近更新: 2021年6月28日

适应症

试验速览

暂无简介。

•1)Patients with bilateral sudden sensorineural hearing loss.
•2)Patients who seek assistance after more than 7 days from the presence of symptoms.
•3)Patients who have already received another treatment for sudden sensorineural hearing loss.
•4)Patients with other causes of sudden sensorineural hearing loss such as autoimmune disease, Meniere disease, use of ototoxic agents, syphilis, trauma.
•5)Acoustic neuroma or demyelinating disease in MRI or other lesion in the cerebellopontine angle.
•6)Patients younger than 18 years old.
•7)Pregnancy.
•8) Contraindications to HBOT such as tension or untreated or recent pneumothorax, administration of certain drugs (Bleomycin, Cisplatin, Disulfiram, Doxorubicin), untreated epilepsy or seizures, congenital spherocytosis, upper respiratory infection, heart failure, chronic obstructive pulmonary disease, claustrophobia.
•9)Glaucoma.
•10)Mental disorders.
•11)Middle ear disease.
•12)Diabetes mellitus.
•13)Difficult to treat hypertension.
•14)Contraindications of steroids administration (peptic ulcer disease, osteoporosis, immunosuppression).

发起方

Medical School of Aristotle University of Thessaloniki