Comparative study of intravenous norepinephrine and mephentermine for maintenance of blood pressure during spinal anaesthesia for caesarean section.
Phase 4
- Conditions
- Health Condition 1: O748- Other complications of anesthesiaduring labor and delivery
- Registration Number
- CTRI/2023/11/059993
- Lead Sponsor
- Department of Anaesthesiology SMS Medical College And Attached Hospitals Jaipur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Elective lower segment caesarian section who have given written and informed consent. 2.Age group- 18-35 years. 3.ASA (American Society Of Anaesthesiologist) grade one and grade two. 4.Weight- 50-80 kg. 5.Height 140-160 cm.
Exclusion Criteria
1.Allergy to study drugs.
2.Contraindications to spinal anaesthesia such as raised ICT,infection at injection site,space occupying lesions of brain and hypovolemia.
3.Parturients with hypertensive disorders of pregnancy,cerebrovascular,hepatic,renal,endocrinological disease.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Mean of number of boluses of Mephentermine and Norepinephrine required to treat hypotension. <br/ ><br>2.Mean of Response % of systolic blood pressure after first bolus doses of Mephentermine v/s Norepinephrin.Timepoint: Just after spinal hyotension, <br/ ><br>At 1 minute till 5 minutes <br/ ><br>At 2 minute inteval till 15 minutes <br/ ><br>At 5 minute interval till 30 minutes
- Secondary Outcome Measures
Name Time Method 1.Mean of systolic blood pressure <br/ ><br>2.Mean of diastolic blood pressure <br/ ><br>3.Mean of mean arterial pressure <br/ ><br>4.Mean of heart rate maternal <br/ ><br>5.Mean of neonatal APGAR scores in both groups.Timepoint: Just after spinal hyotension, <br/ ><br>At 1 minute till 5 minutes <br/ ><br>At 2 minute inteval till 15 minutes <br/ ><br>At 5 minute interval till 30 minutes