NL-OMON42212招募中不适用
Clinical, experimental, and genetic studies on the etiology of central serous chorioretinopathy - Studies on the etiology of central serous chorioretinopathy
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 825
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •All participants will be aged above 18 years.;1) Genetic analysis and ophthalmological examination in a CSC patient cohort, and in known families with CSC.
- •* Sporadic CSC: CSC patients who visit or visited the outpatient clinic of the Department of Ophthalmology in either the Leiden University Medical Center or the Rotterdam Eye Hospital.
- •* Familial CSC: CSC patients, who have at least one family member in whom CSC has been detected. ;2) Analysis of serum complement activity in CSC patients and in a healthy control group.
- •* CSC patients who visit the outpatient clinic of the Department of Ophthalmology in the Leiden University Medical Center. Per patient a control will be recruited. For example, the husband or wife of each CSC patient who visits the outpatient clinic of the department of Ophthalmology.;3) Endocrinological analysis of cortisol and testosterone exposure and sensitivity in CSC patients and in controls.
- •* CSC patients who visit the outpatient clinic of the Department of Ophthalmology in the Leiden University Medical Center will be referred to the outpatient clinic of the Department of Endocrinology. ;4) Analysis of the retinal phenotype and choroidal thickness in patients with Cushing*s syndrome, Conn*s syndrome, patients who receive solumedrol (a corticosteroid) during acute rejection of a renal transplant, or post renal transplantation patients who receive corticosteroids.
- •* Patients with Cushing*s syndrome or Conn*s syndrome who visit or visited the outpatient clinic of the Department of Endocrinology and are willing to take part in this study.
- •* Patients receiving solumedrol during acute rejection of a renal transplant, or post renal transplantation patients who receive corticosteroids, who visit or visited the outpatient clinic of the Department of Nephrology and are willing to take part in this study.
排除标准
- •For our study no exclusion criteria are applicable.
研究者
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