Genetic immunological causes of recurrent miscarriages; 'HLA sharing as a cause of recurrent miscarriages'

Recruiting

• Conditions: Abortions; Recurrent miscarriages; 10000211

• Registration Number: NL-OMON39578
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 432

Inclusion Criteria

Recurrent miscarriages (>2 and < 20 weeks)
Age < 36 years

Exclusion Criteria

Parental chromosomal abnormalities
Uterus anomalies

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Distribution and prevalence of: HLA sharing, KIR genotype, polymorphism of<br /><br>progesteronreceptor, mutations of complement regulatory genes and HLA<br /><br>antibodies</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Pregnancy-outcome and complications</p>