Study of intermittent fasting to check whether it can cause weight loss improve liver function and quality of life and normalise blood pressure in fatty liver patients when compared to those not following intermittent fasting
Phase 2
- Conditions
- Health Condition 1: E660- Obesity due to excess calories
- Registration Number
- CTRI/2024/02/062783
- Lead Sponsor
- on funded study All India Institute of medical sciences jodhpur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Diagnosed case of metabolic syndrome and or Nonalcoholic fatty liver disease
Age between 18 and 75 years
Body mass index of greater than or equal to 25 kilogram per metre square
Exclusion Criteria
Pregnancy or lactation
Inherited or acquired immunodeficiency
On immunosuppressive drugs
On insulin or insulin secretagogues
Malignancies
Mental illness
Chronic kidney disease with estimated glomerular filtration rate eGFR less than or equal to30
Aspartate aminotransferase or Alanine transaminase more than three times the upper limit of normal
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method iver function tests at baseline and at 12 weeksTimepoint: Liver function tests at baseline and at 12 weeks
- Secondary Outcome Measures
Name Time Method <br/ ><br>weight loss in terms of Body Mass IndexTimepoint: At baseline and after 3 months;Fasting lipid profileTimepoint: At baseline and after 3 months;mean blood pressureTimepoint: At baseline and after 3 months;quality of life through a questionnaire of patients included in the study QOL will be assessed using the WHO BREF questionnaire.Timepoint: At baseline and after 3 months