JPRN-UMIN000004569
Completed
Phase 4
Study of assessment for vascular endothelial function and renal function with irbesartan or amlodipine in hypertensive patients with proteinuria - prospective randomized controlled trial - - Study of assessment for vascular endothelial function and renal function with irbesartan or amlodipine in hypertensive patients with proteinuria - prospective randomized controlled trial
ConditionsHypertension with proteinuria
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Hypertension with proteinuria
- Sponsor
- Hokkaido University Hospital
- Enrollment
- 40
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1\) history of anaphylaxis of irbesartan or amlodipine, 2\) patients who did not receive an antihypertensive treatment with angiotensin II receptor blockers (ARB), angiotensin converting enzyme (ACE) inhibitors or rennin inhibitor before the enrollment, 3\) secondary hypertension, 4\) history of stroke, myocardial infarction or cardiovascular disease, 5\) nephrosis, 6\) genetic renal disease, 7\) patients with nephritis treated by corticosteroids, 8\) hepatic dysfunction, 9\) moderate heart failure (New York heart Association classes II or more), 10\) patients with cancer or severe disease, 11\) uncontrolled diabetic mellitus (HbA1c 8\.0% or more), 12\) bronchial asthma, 13\) pregnancy, 14\) patients who are inadequate to enter this study due to the other reasons by physician's judgments
Outcomes
Primary Outcomes
Not specified
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