Cardiac Arrhythmias and Dysfunction in the Pediatric Burn Patient
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Frequency of cardiac dysfunction in pediatric burn patients
研究概览
简要总结
The purpose of this study is to collect information about how often an abnormal heart beat happens in children who have been burned.
详细描述
The investigators hope to learn the following:
- If heart arrhythmias are more common in children with a large burn injury than in children with a small burn injury.
- The difference in development of a heart arrhythmia after a large burn injury by comparing information from children with large burns who do and do not develop a heart arrhythmia.
- A better understanding of the length of a hospital stay, the number of operations, and the number of care complications in patients with heart arrhythmias after a burn injury.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Factorial
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- — 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Pediatric burn patients from age 0 - 18 who have sustained a burn injury will be eligible for this study.
- •Group 1 will consist of patients with ≥30% TBSA burn injury. Group 2 will consist of patients with <30% TBSA burn injury who develop a cardiac abnormality.
排除标准
- •Patients with pre-existing cardiac disorder, desquamative skin disorders and electrical injury.
研究组 & 干预措施
≥30% TBSA burn injury
For patients in Group 1 with ≥30% TBSA, a baseline Echocardiogram (ECHO) will be obtained approximately one week from admission and monthly (+/- 1 week) or at an interval determined by cardiology during the acute inpatient stay. ECHO tests will be discontinued after 3 negative exams or when discontinued by cardiology, whichever comes first.
干预措施: Echocardiogram (Diagnostic Test)
<30% TBSA burn injury
For patients in Group 2 with <30% TBSA and presence of a cardiac abnormality standard clinical care appropriate for the type of arrhythmia will be followed.
结局指标
主要结局
Frequency of cardiac dysfunction in pediatric burn patients
时间窗: Through study completion up to 4 years after hospital discharge.
Results of echocardiograms will be compared between patients with cardiac dysfunction versus those without cardiac dysfunction.
次要结局
- Acute care hospital length of stay(Hospital admission to discharge (average of 1 day per %TBSA burn - example 30 days for a 30% TBSA burn injury).)
研究者
Ivan Wilmot
Principal Investigator
Shriners Hospitals for Children