NL-OMON36346招募中不适用
Capsaicin induced neurogenic inflammation of the skin: influence of migraine and estrogen level - Capsaicin, estrogen and migrain
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 66
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Age between 18 and 75 years
- •Non-smoking for > 6 months
- •Body mass index between 18 and 30
- •Capable and willing to give informed consent
- •General good health, based on medical history and physical examination;Subjects with migraine:
- •Should have diagnosed migraine, fulfilling criteria 1.1. Migraine without aura of International Classification of Headache Disorders (ICHD).
- •Migraine attacks should occur exclusively on day 1±2 (ie, days -2 to +3) of menstruation in at least two out of three menstrual cycles and additionally at other times of the cycle.
- •Should have a natural and regular menstrual cycle
- •Age between 18 and 45 years;Subjects without migraine:
- •Should have a natural and regular menstrual cycle
- •Age between 18 and 45 years
- •Postmenopausal subjects
- •Should be amenorrhoeic for at least 1 year
排除标准
- •Use of hormonal contraceptives or hormonal replacement therapy
- •History of cardiovascular disease
- •Any serious illness that can compromise study participation
- •Regular use of medication outside the period of migraine attacks
- •Dermal diseases at the upper frontal side of the face
- •Pregnancy or breastfeeding
- •History of sensitivity to the fruits of capsicum plants (eg chilli peppers)
- •Alcohol or drug abuse
研究者
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