Surgical timing after radiotherapy for rectal cancer
Completed
- Conditions
- Topic: National Cancer Research Network, Generic Health Relevance and Cross Cutting ThemesSubtopic: Colorectal Cancer, Rectum, SurgeryCancerMalignant neoplasm of rectum
- Registration Number
- ISRCTN88843062
- Lead Sponsor
- Yeovil District Hospital (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
1. Age 18 years or over
2. Completing neo-adjuvant long-course
3. Chemoradiotherapy for rectal cancer
4. Fit for surgical resection by open or laparoscopic anterior resection or abdominoperineal excision (APE)
5. American Society of Anaesthesiology (ASA) grades I, II and III
6. Able and willing to provide written consent
7. Target Gender: Male & Female
Exclusion Criteria
1. Emergency admission or bowel obstruction/perforation
2. Short course radiotherapy regime
3. Anal cancer
4. Metastatic disease
5. Previous palliative pelvic radiotherapy
6. Rectal cancer on top of inflammatory bowel disease
7. Contra-indication to Magnetic Resonance Imaging scanning
8. Poor cognitive ability and/or unable to provide consent
9. Pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Operative Technical Complexity measured at time of surgical intervention
- Secondary Outcome Measures
Name Time Method