The Effect of Video and Traditional Laryngoscopy on Hemodynamic Response in Hypertensive and Normotensive Patients

Not Applicable

Completed

• Conditions: Hypertension; Intubation; Anesthesia
• Interventions: Device: C-Mac Videolaryngoscope; Device: Macintosh laryngoscopy

• Registration Number: NCT03376828
• Lead Sponsor: Aydin Adnan Menderes University

Brief Summary

During endotracheal intubation, it is known that la laryngoscopy has significant effects, such as tachycardia and blood pressure increase, which may be harmful, especially in those with cardiovascular disease. Different studies comparing laryngeal stimulation and there resulting hemodynamic response made with various intubation devices are available in the literature. The investigators planned to work with the hypothesis that endotracheal intubation with videolaryngoscopy would have less hemodynamic response traditional (Macintosh) laryngoscopy and the use of videolaryngoscopy would result in wider vision with less laryngeal stimulation.

Detailed Description

In this study, in a study on endotracheal intubation under general anesthesia, a routine preparation of endotracheal intubation using video laryngoscopy or Macintosh laryngoscopy in adult hypertensive and normotensive patients between 18-75 years old, form will be written and recorded.

Patient age, weight, height, sex, operation, co-morbid conditions and vital findings, measurements used in airway evaluation, initial trial success, laryngoscope using number of procedures, intubation tube number will be recorded.

Statistical analysis was performed using statistical program to compare the hemodynamic response of hypertensive and normotensive patients using videolaryngoscope or Macintosh laryngoscope

Study Timeline

• Study Start: 2016-05-25
• Study First Submitted: 2017-12-06
• Study First Submitted QC: 2017-12-13
• Study First Posted: 2017-12-19
• Primary Completion: 2018-05-25
• Study Completion: 2018-05-25
• Status Verified: 2018-12
• Last Update Submitted: 2018-12-24
• Last Update Posted: 2018-12-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Age: 18-75 years.
• Underwent surgery under general anesthesia.

Exclusion Criteria

• ASA (American Society of Anesthesiologists) IV, V patients
• Preoperative systolic blood pressure 180 mmHg, diastolic blood pressure a pressure above 110 mmHg.
• Ejection fraction is less than 40%.
• Difficult intubation history
• Mallampati 3,4

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Hypertensive VL group	C-Mac Videolaryngoscope	Hypertensive VL group: Patients participating in the study were randomly assigned hypertensive (preoperative systolic blood pressure \<180 mmHg and diastolic blood pressure \<100 mmHg) C-Mac Videolaryngoscope using intubated
Non-hypertensive T group	Macintosh laryngoscopy	Non-hypertensive T group: (Preoperative systolic blood pressure \< 140 mmHg and diastolic blood pressure \< 100 mmHg) Macintosh laryngoscopy using intubated
Non-hypertensive VL group	C-Mac Videolaryngoscope	Non-hypertensive VL group: Preoperative systolic blood pressure \< 140 mmHg and diastolic blood pressure \< 100 mmHg C-Mac Videolaryngoscope using intubated
Hypertensive T group	Macintosh laryngoscopy	Hypertensive T group: Patients participating in the study were randomly assigned hypertensive (preoperative systolic blood pressure \<180 mmHg and diastolic blood pressure \<100 mmHg) Macintosh laryngoscopy using intubated

Primary Outcome Measures

Name	Time	Method
Hemodynamic response	0-10 minute	Change from baseline noninvasive blood pressure and heart rate

Secondary Outcome Measures

Name	Time	Method
intubation time	0-120 seconds	The time elapsed between the passage of the laryngoscopy through the teeth to teeth
Glottic view grade	During intubation	Using the Cormack Lehane score

Trial Locations

Locations (1)

Adnan Menderes University Training and Research Hospital; 🇹🇷 Aydın, Turkey