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临床试验/CTRI/2025/07/091904
CTRI/2025/07/091904尚未招募不适用

Comparison of Calf Muscle Strength and Endurance among smokers and Non Smokers

Saisha kamat1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年8月8日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
Heel raise test

研究概览

简要总结

This observational, cross-sectional study aims to compare calf muscle strength and endurance between smokers and non-smokers aged 20–50 years using the Single-Leg Heel Raise Test. Conducted at SDM College of Physiotherapy, Dharwad, the study will include 60 participants divided into two groups: smokers (with at least 1 year of daily smoking and a minimum of 5 pack-years) and non-smokers (no history of smoking or passive exposure). Individuals with respiratory, neuromuscular, cardiovascular, metabolic disorders, or recent lower limb injuries will be excluded. The primary outcome is the number of correct heel raises performed until the participant is exhausted. The test will be stopped when participants are unable to (1) raise the stance heel from the incline or repeat a full heel-rise cycle, (2) keep the pace, knee angle, or trunk position constant, or (3) use the wall to help with performance and rely on fingertip support for balance. Secondary analysis will explore correlations between smoking exposure (duration, intensity, pack-years) and muscle function. Data will be analyzed using independent t-tests and correlation statistics, with ethical approval to be obtained prior to the study.

研究设计

研究类型
Observational

入排标准

年龄范围
20.00 Year(s) 至 50.00 Year(s)(—)
性别
All

入选标准

  • Age between 20 and 50 years.
  • For smokers: minimum of 1 year of daily smoking with at least 5 pack-years history.
  • For non-smokers: no history of smoking or passive smoking.
  • Ability to perform physical tests without aid.
  • BMI between 18.5–29.9 kg/m² to minimize confounding from obesity or malnutrition.
  • Willingness to participate with informed consent.

排除标准

  • Diagnosed chronic respiratory illness (COPD, asthma, bronchiectasis, etc.) and PVD.
  • History of cardiovascular or neuromuscular disorders affecting lower limb function.
  • Recent lower limb injury or surgery (less than 6 months).
  • Diabetes mellitus or other endocrine/metabolic disorders affecting muscle function.
  • Participation in structured lower limb resistance training in the past 3 months.
  • Pregnancy.

结局指标

主要结局

Heel raise test

时间窗: until exhaustion

次要结局

未报告次要终点

研究者

发起方
Saisha kamat
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Saisha Kamat

SDM college of Physiotherapy

研究点 (1)

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