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临床试验/CTRI/2024/12/078478
CTRI/2024/12/078478尚未招募不适用

Randomized Comparative Clinical Study to evaluate the efficacy of Jeerakadi lepa and Manjistha lepa in the Management of Vyangya w.s.r to Melasma

Dr VJD Gramin Ayurved Mahavidyalaya1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2024年12月25日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
80
试验地点
1
主要终点
Symptoms of Vyangya like

研究概览

简要总结

Ayurveda is an eternal life science and the main aim of Ayurveda is promotion of health and eradication of the diseases. The Beauty and Attraction of individual is reflected in the skin’s health. Skin diseases though afflicts bodily but gives lot of psychological disturbances.

Vyanga is the one of the Kshudra Roga, which is characterized by Neeruja (painless), Shyava Varna Mandalas (bluish black patches) occurring especially on the face. While considering the pathogenesis of Vyanga, involvement of Pitta is more and it is Rakta Pradoshaja Vyadhi.

On the basis of clinical features it is correlated with melasma, or facial melanosis, one of the hyper pigmented disorders. Melasma is a common acquired hypermelanosis that affects sun- exposed areas of skin. This study is important since melasma is a disease causing mental side effects in patients, due to darkness and opacity of the skin; therefore, the treatment of melasma in terms of its psychological complication is of particular importance.

Hyperpigmentation (melanosis) is a group of disorders characterized by abnormally darker skin that results from increase in the concentration of pigment, which occurs either due to increased number of melanocytes or increase activity of melanocytes.

Now a day’s Vyanga becomes one of the biggest problems of the society. Many people are suffering from Vyanga today. Among them women are commonly found due to changes occurring during pregnancy and use of cosmetic supplements.

In the context of Vyanga both Shodana and Shamana Chikitsa are explained in the form of Raktamokshana, Lepa, Abhyanga and oral medication".

Need of the study -

Pigmentation are seen especially on cheeks, nose, forehead and chin. The Prevalence of melasma varies between 1.5% and 33.3% depending on the population. Its Prevalence in women is around 50%- 70% in Pregnancy stage. In men its 20.5-25.38% of the cases.

Acharya charaka has broadly classified chikitsa under three main headings, namely Antah Parimarjana, Bahir Parimarjana and Shastra Prranidhana. Lepa kalpana is the Upakalpana, which comes under Bahir Parimarjana Chikitsa . The Lepa which is applied on the face gives strength to the muscle of eyes, cheeks has to be thick which enhance face complexion which in turns cures Vyanga. Alepa normalizes Rakta and Pitta.

So, the Lepa which is one of the forms of external application for skin diseases is taken for this study. Jeerakadi Lepa & Manjishtha Lepa is mentioned in the Ashtanga Hrudaya Chikitsathana for the management of Vyanga Chikitsa.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
None

入排标准

年龄范围
20.00 Year(s) 至 50.00 Year(s)(—)
性别
All

入选标准

  • 1.Patients having clinical features of Vyanga.
  • 2.Patients willing to sign the informed consent form.
  • 3.Patient of either gender, irrespective of socioeconomic status.
  • 4.Patients not using any topical treatment for melasma prior to enrollement in study.

排除标准

  • 1.Patients taking O.C.Pills.
  • 2.Patients suffering from other skin disorder and other systemic disorder.
  • 3.Patients associated with any serious systemic disorders.
  • 4.History of Allergy to topical application.
  • 5.Cancer of skin.

结局指标

主要结局

Symptoms of Vyangya like

时间窗: 7,14,21,28 Days Symptoms will be Observed

1. Black spot

时间窗: 7,14,21,28 Days Symptoms will be Observed

2.Brown spot

时间窗: 7,14,21,28 Days Symptoms will be Observed

3.itching

时间窗: 7,14,21,28 Days Symptoms will be Observed

All the above symptoms Will be decreased and control over Vyangya with reference to 2.melasma

时间窗: 7,14,21,28 Days Symptoms will be Observed

次要结局

  • Decreased in symptoms of Vyangya & hyperpigmmantion(Like darkness black spot)

研究者

发起方
Dr VJD Gramin Ayurved Mahavidyalaya
申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Dr Mahesh Kishan Warwade

Dr VJD Gramin ayurved mahavidyalaya patur

研究点 (1)

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