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临床试验/NCT04277481
NCT04277481Unknown不适用

The Acute Effect of Cold Pack Therapy Applied on Healthy People for Different Periods on the Mechanical Properties of the Quadriceps Muscle

Acibadem University1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2020年2月12日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
60
试验地点
1
主要终点
Evaluation of the mechanical properties of the muscle-1

研究概览

简要总结

The cold pack application, which is a special silicate gel impregnated with water in a soft rubber envelope, is frequently applied in the clinic. It has been shown in the literature that local cold application causes increased resistance to movement. It is also reported that the muscle can change its mechanical properties in a short time. However, the effect of the cooling package application applied in different periods on the mechanical properties of the muscle is unknown. Therefore, in the current study proposal, the investigators aim to investigate the acute effect (0 min, 5 min, 10 min, 15 min, 20 min and 30 min) of cold pack therapy applied on healthy individuals for different periods (10-12-15-20 minutes).

详细描述

Cold Packs (Cold Pack, CP); Slika gel packs are the most commonly used modalities in clinics. Special silicate gel impregnated with water in a soft rubber envelope is stored in coolers whose temperature is maintained between -12.2 ° C and 9.4 ° C . There are different sizes and shapes. Since it does not lose its softness when it is cooled, it adapts well to the folds of the body. By putting a towel between the skin and the package, a homogeneous cooling is tried to be achieved, hygiene is provided and it is easier to tolerate the feeling of extreme cold felt in the first contact of the cold package. It can be applied for a relatively long time without losing its cold due to its low conductivity. Significant increase in package temperature is seen from the 15th minute of the application. It is stated that it decreases the skin temperature up to 10 ° C and keeps it at 20 ° C-30 ° C for 3 hours depending on the room temperature. They can be used repeatedly by cooling .

Intensive cold application for 12-15 minutes is enough to reduce pain and muscle spasm . It has also been shown that a cold application over 30 minutes can cause cold bite and nerve problems . However, in practical applications, cold appears to vary between 15-30 minutes for pain, muscle spasm and edema . In a review made by Auley regarding cryotherapy treatments; ice application has been shown to be used in 5 to 85 minutes in many studies. They said that cold application does not have a specified frequency and duration, but repeated 10 minutes of cold application is effective. In addition, it has been reported that there is evidence of a slightly less drop from 10 minutes to 20 minutes while the temperature drops in the first 10 minutes .

In animal studies performed in vitro, although muscle tissue has reported high resistance to strain after cooling, direct mechanical responses to muscles in human studies There is only one study that evaluates. In this study carried out by Mustalampi et al., Parameter measurements indicating the mechanical properties of the muscle immediately after applying the cold pack applied locally to the quadriceps muscle for 20 minutes and after 15 minutes. As a result of the study, the muscle has become stiffer, less elastic in terms of mechanical properties and it has been shown that these changes do not completely recover after 15 minutes. It was not observed when it was reinstated after fifteen minutes.

In the light of this information, in the current study proposal; the investigators aim to investigate the acute effect (0 min, 5 min, 10 min, 15 min, 20 min and 30 min) of the cold pack therapy on the mechanical properties of the quadriceps muscle in healthy people for different periods (10-12-15-20 minutes).

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 23 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • Volunteer student between the ages of 18-23 with a subcutaneous fold thickness of the quadriceps muscle between 5 mm and 15 mm.
  • Non-smoker
  • No drug use

排除标准

  • Having any cardiovascular or peripheral vascular disease
  • Known neuromuscular pathology history
  • Having diabetes mellitus disease
  • Having a history of lower limb pain and previous surgery
  • Has a history of insensitivity to local heat or cold

结局指标

主要结局

Evaluation of the mechanical properties of the muscle-1

时间窗: Change from Baseline mechanical properties at 0 minute, 10 minute, 20 minute past- cold pack

Viscoelastic stiffness \[N/m\] will be measured in MyotonPro 3 (MYO, Tallin, Estonia).

Evaluation of the mechanical properties of the muscle-3

时间窗: Change from Baseline mechanical properties at 0 minute, 10 minute, 20 minute past- cold pack

Mechanical stiffness (N/m) will be measured in MyotonPro 3 (MYO, Tallin, Estonia).

Measurement of skin temperature

时间窗: Change from Baseline skin temperature at 0 minute, 5 minute, 10 minute, 20 minute past- cold pack

For thermal imaging, a 120-9-90 pixel resolution FLIR E5 camera thermal camera (FLIR Systems AB, Sweden) will be used, and Color Palette iron will be selected to display images. The video will be taken from a distance of 1 m at a speed of 8 photos / s.

Evaluation of the mechanical properties of the muscle-2

时间窗: Change from Baseline mechanical properties at 0 minute, 10 minute, 20 minute past- cold pack

Oscillation frequency (Hz) will be measured in MyotonPro 3 (MYO, Tallin, Estonia).

次要结局

未报告次要终点

研究者

发起方
Acibadem University
申办方类型
Other
责任方
Sponsor

研究点 (1)

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