Evaluation of the effect of Angiotensin ll receptor blocker for plaque vulnerability after percutaneous coronary intervention (PCI)
Phase 4
- Conditions
- Hypertension with coronary artery disease
- Registration Number
- JPRN-UMIN000001720
- Lead Sponsor
- The University of Tokushima, Cardiovascular Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
1) Previous storoke<=6month 2) Ejection fraction<=40% 3) Patients with dialysis 4) Diabetic patients with HbA1c<=6.5 5) Patients who are treated with statin except pravastatin sodium
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in plaque composition and observation by Integrated Backscatter Intravascular Ultrasound (IB-IVUS)
- Secondary Outcome Measures
Name Time Method 1) Change in surrogate marker in coronary vein blood hs-CRP,IL-6,TNF-alpha,IP-10,MMP-3, MMP-9,MCP-1,MIF,PTX-3,Heparin cofactor 2) Office blood pressure