A study to compare the benefits of using cord blood serum eye drop versus heparin eye drops versus applying amniotic membrane on acute Stevens Johnson Syndrome patients eyes to reduce inflammation and improve visio
Not Applicable
- Conditions
- Health Condition 1: O- Medical and SurgicalHealth Condition 2: L511- Stevens-Johnson syndrome
- Registration Number
- CTRI/2024/07/071587
- Lead Sponsor
- Dr R.P.Centre for Ophthalmic Sciences, AIIMS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
a)Patients diagnosed with acute SJS with ocular involvement.
b)Aged 18 years or older.
c)Willing to provide informed consent
Exclusion Criteria
a)Patients with a history of pre-existing ocular conditions that could interfere with the study results.
b)Patients with known allergies to any of the study components.
c)Pregnant or lactating women
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement in best corrected visual acuity (BCVA)Timepoint: Day 0, Day 3, Day 7, Day 14, Day30, Day 60, Day 90, Day 120, Day 150, Day 180.
- Secondary Outcome Measures
Name Time Method 1. Ocular pain and discomfort (OSDI questionnaire) <br/ ><br>2. Severity scoring of ocular manifestations (Gregory et al grading system)Timepoint: Day 0, Day 3, Day 7, Day 14, Day30, Day 60, Day 90, Day 120, Day 150, Day 180.