Combined tDCS and Vision Restoration Training in Subacute Stroke Rehabilitation: A Pilot Study
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Hemianopia
- Sponsor
- University of Magdeburg
- Enrollment
- 14
- Locations
- 2
- Primary Endpoint
- Change of mean sensitivity (in dB) detection threshold from baseline to post-intervention
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
The purpose of this Study is to determine whether non-invasive transcranial direct current stimulation (tDCS) is effective in increasing rehabilitation effects after stroke in visual Cortex.
Detailed Description
Visual field defects after posterior cerebral artery stroke can be improved by vision restoration training (VRT), but when combined with transcranial direct current stimulation (tDCS) which alters brain excitability, vision restoration can be potentiated in the chronic stage. Because it is possible that such therapy may be more effective during the early recovery phase after the stroke and can reach patients during the rehabilitation phase, investigators wished to explore the applicability, efficacy and safety of early intervention with a combined tDCS/VRT treatment. Seven post-acute stroke homonymous hemianopia patients were assigned to 10 sessions of combined tDCS (2mA, 10 daily sessions of 15-20 min) and VRT. The primary outcome criterion was the pre-post change in perimetric detection thresholds in percent. The results were compared to 7 age and stroke lesion matched controls of our patient data pool who received standard rehabilitation.
Investigators
Bernhard A. Sabel
Professor
University of Magdeburg
Eligibility Criteria
Inclusion Criteria
- •Posterior Cerebral Artery Stroke
- •Visual Field Defect
- •Lesion age 4 weeks up to 6 month max
Exclusion Criteria
- •Electrical Implants
- •Metal artefacts in head
- •Visual Neglect
Outcomes
Primary Outcomes
Change of mean sensitivity (in dB) detection threshold from baseline to post-intervention
Time Frame: 14-20 days post treatment,