Evaluation of the effectiveness of Berberis integerrima and Thyme essential oil in the treatment of acne

Phase 3

• Conditions: Acne vulgaris.; L70.0; Acne vulga

• Registration Number: IRCT20150721023282N21
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 29 November 2021

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Mild acne vulgaris. Mild acne is defined as non-inflammatory lesions (comedones), a few inflammatory (papulopustular) lesions, without nodules and cysts.
Moderate acne vulgaris. Moderate acne is defined as more inflammatory lesions, with or without comedones, without nodules and cysts.

Exclusion Criteria

Receiving systemic anti-acne treatment during last three months
Receiving oral anti-acne treatment during last one month
Receiving systemic antibiotics during last one month
Receiving antiandrogen medicine during last three months
Hepatic or renal disorder
Endocrine disorders
Receiving oral contraceptive during last one month
Other skin disorders or infection
Pregnancy
Lactation
Consumption of any drugs that induce acne
Alcohol or substance abuse

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Percentage change in mGAGS scale at the end of the intervention. Timepoint: Before the intervention, 28 days after the start of intervention. Method of measurement: Visio Face - Camera.;Change the number of lesions at the end of the intervention. Timepoint: Before the intervention, 28 days after the start of intervention. Method of measurement: Visio Face - Camera.;Change of the number of lesions based on the type of lesion at the end of the intervention. Timepoint: Before the intervention, 28 days after the start of intervention. Method of measurement: Visio Face - Camera.

Secondary Outcome Measures

Name	Time	Method
umber of people with complete recovery at the end of the intervention. Timepoint: Before the intervention, 28 days after the start of intervention. Method of measurement: Observation.;Time required for complete recovery. Timepoint: Before the intervention, 28 days after the start of intervention. Method of measurement: Observation.