Interest of the Induction With Target-controlled Inhalation of Sevoflurane on Spikes Wave Occurrence

Not Applicable

Completed

• Conditions: General Anesthesia
• Interventions: Drug: Induction with Sevoflurane

• Registration Number: NCT00775879
• Lead Sponsor: University Hospital, Bordeaux

Brief Summary

Sevoflurane is widely used for induction of anaesthesia. Several studies showed EEG abnormalities during mask induction with sevoflurane. The aim of our study was to test the induction target concentration of sevoflurane on the spikes wave occurrence.

Detailed Description

Not available

Study Timeline

• Study Start: 2006-03
• Primary Completion: 2008-07
• Study Completion: 2008-07
• Study First Submitted: 2008-10-17
• Study First Submitted QC: 2008-10-17
• Study First Posted: 2008-10-20
• Status Verified: 2013-05
• Last Update Submitted: 2013-05-17
• Last Update Posted: 2013-05-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 34

Inclusion Criteria

• programmed gynecological surgery
• ASA 1 or 2

Exclusion Criteria

• arterial hypertension
• gastro-oesophageal reflux
• pregnancy
• diabetes
• obesity
• asthma
• tobacco

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
A	Induction with Sevoflurane	2.5% target concentration
B	Induction with Sevoflurane	2.5% manually selected

Primary Outcome Measures

Name	Time	Method
Incidence of spike wave	during anaesthesia induction with sevoflurane