Titration of Volatile Anesthetic with Brain Function Monitoring for Prevention of Pediatric Anesthesia Emergence Delirium: A Randomized Controlled Trial

Not Applicable

• Conditions: General Anesthesia; Anesthesia, General

• Registration Number: JPRN-jRCTs032210248
• Lead Sponsor: Kasuya Shugo

Brief Summary

EEG-guided titration of anesthesia greatly reduced exposure to sevoflurane, leading to a reduced incidence of PAED, shorter recovery times and reduced length of stay in the PACU.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-08-17
• Study Completion: 2023-03-18
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 177

Inclusion Criteria

Scheduled surgical procedure under general anesthesia for more than 30 minutes
Age 1 to 6
Procedure with minimal or easilly controlled postoperative pain

Exclusion Criteria

Unable to place EEG sensor (e.g. abnormal skin, interference with surgical field)
Neurological condition affecting evaluation of EEG or mental state
Exclusion by discretion of anesthesiologist

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pediatric Anesthesia Emergence Delirium (PAED) Score

Secondary Outcome Measures

Name	Time	Method
Amount of exposure to anesthetic agent