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临床试验/NCT05909007
NCT05909007已完成不适用

Post-operative Thoracic Epidural Analgesia and Incidence of Major Complications: a Large Retrospective Dual Center Experi-ence

AHEPA University Hospital1 个研究点 分布在 1 个国家目标入组 1,145 人开始时间: 2012年4月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
1,145
试验地点
1
主要终点
incidence of major complications

研究概览

简要总结

A retrospective observational dual center study investigating side effects and major complications after thoracic epidural insertion according to local safety protocols.

详细描述

Abstract: (1) Background: Thoracic epidural analgesia is considered the gold standard in post-operative pain management following thoracic surgery. This study was designed to explore the safety of thoracic epidural analgesia and to quantify the incidence of its post-operative side-effects in patients undergoing thoracotomy for major surgery, such as resection of lung malignancies and lung transplantation. (2) Methods: This is a retrospective, dual-center observa-tional study implementing patients that underwent major thoracic surgery including lung trans-plantation and received concurrent placement of thoracic epidural catheters for postoperative an-algesia. An electronic system of referral and documentation of complications was used, and information was retrieved from our electronic critical care charting system. Side effects such as nausea and vomiting , itching, catheter related issues and also major complications such as epidural haematoma, abscess, or permanent nerve damage were investigated.

The study aims to highlight the importance of a solid documentation and recording system alongside with the implementation of safety protocols.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
20 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All patients undergoing major thoracic surgery ASA1-3
  • All patients undergoing lung transplantation

排除标准

  • Active bleeding
  • Coagulopathy
  • High inflammatory markers
  • Lack of patients' consent for throracic epidural insertion

结局指标

主要结局

incidence of major complications

时间窗: 3 YEARS

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

DESPOINA SARRIDOU

Assistant Professor of Anaesthesia

AHEPA University Hospital

研究点 (1)

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