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Clinical Trials/NCT05909007
NCT05909007
Completed
Not Applicable

Post-operative Thoracic Epidural Analgesia and Incidence of Major Complications: a Large Retrospective Dual Center Experi-ence

AHEPA University Hospital1 site in 1 country1,145 target enrollmentApril 2012

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Neuropathic Pain
Sponsor
AHEPA University Hospital
Enrollment
1145
Locations
1
Primary Endpoint
incidence of major complications
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

A retrospective observational dual center study investigating side effects and major complications after thoracic epidural insertion according to local safety protocols.

Detailed Description

Abstract: (1) Background: Thoracic epidural analgesia is considered the gold standard in post-operative pain management following thoracic surgery. This study was designed to explore the safety of thoracic epidural analgesia and to quantify the incidence of its post-operative side-effects in patients undergoing thoracotomy for major surgery, such as resection of lung malignancies and lung transplantation. (2) Methods: This is a retrospective, dual-center observa-tional study implementing patients that underwent major thoracic surgery including lung trans-plantation and received concurrent placement of thoracic epidural catheters for postoperative an-algesia. An electronic system of referral and documentation of complications was used, and information was retrieved from our electronic critical care charting system. Side effects such as nausea and vomiting , itching, catheter related issues and also major complications such as epidural haematoma, abscess, or permanent nerve damage were investigated. The study aims to highlight the importance of a solid documentation and recording system alongside with the implementation of safety protocols.

Registry
clinicaltrials.gov
Start Date
April 2012
End Date
November 2014
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

DESPOINA SARRIDOU

Assistant Professor of Anaesthesia

AHEPA University Hospital

Eligibility Criteria

Inclusion Criteria

  • All patients undergoing major thoracic surgery ASA1-3
  • All patients undergoing lung transplantation

Exclusion Criteria

  • Active bleeding
  • Coagulopathy
  • High inflammatory markers
  • Lack of patients' consent for throracic epidural insertion

Outcomes

Primary Outcomes

incidence of major complications

Time Frame: 3 YEARS

Study Sites (1)

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