Post-operative Thoracic Epidural Analgesia and Incidence of Major Complications: a Large Retrospective Dual Center Experi-ence
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Neuropathic Pain
- Sponsor
- AHEPA University Hospital
- Enrollment
- 1145
- Locations
- 1
- Primary Endpoint
- incidence of major complications
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
A retrospective observational dual center study investigating side effects and major complications after thoracic epidural insertion according to local safety protocols.
Detailed Description
Abstract: (1) Background: Thoracic epidural analgesia is considered the gold standard in post-operative pain management following thoracic surgery. This study was designed to explore the safety of thoracic epidural analgesia and to quantify the incidence of its post-operative side-effects in patients undergoing thoracotomy for major surgery, such as resection of lung malignancies and lung transplantation. (2) Methods: This is a retrospective, dual-center observa-tional study implementing patients that underwent major thoracic surgery including lung trans-plantation and received concurrent placement of thoracic epidural catheters for postoperative an-algesia. An electronic system of referral and documentation of complications was used, and information was retrieved from our electronic critical care charting system. Side effects such as nausea and vomiting , itching, catheter related issues and also major complications such as epidural haematoma, abscess, or permanent nerve damage were investigated. The study aims to highlight the importance of a solid documentation and recording system alongside with the implementation of safety protocols.
Investigators
DESPOINA SARRIDOU
Assistant Professor of Anaesthesia
AHEPA University Hospital
Eligibility Criteria
Inclusion Criteria
- •All patients undergoing major thoracic surgery ASA1-3
- •All patients undergoing lung transplantation
Exclusion Criteria
- •Active bleeding
- •Coagulopathy
- •High inflammatory markers
- •Lack of patients' consent for throracic epidural insertion
Outcomes
Primary Outcomes
incidence of major complications
Time Frame: 3 YEARS