Post-operative Thoracic Epidural Analgesia and Incidence of Major Complications: a Large Retrospective Dual Center Experi-ence
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,145
- 试验地点
- 1
- 主要终点
- incidence of major complications
研究概览
简要总结
A retrospective observational dual center study investigating side effects and major complications after thoracic epidural insertion according to local safety protocols.
详细描述
Abstract: (1) Background: Thoracic epidural analgesia is considered the gold standard in post-operative pain management following thoracic surgery. This study was designed to explore the safety of thoracic epidural analgesia and to quantify the incidence of its post-operative side-effects in patients undergoing thoracotomy for major surgery, such as resection of lung malignancies and lung transplantation. (2) Methods: This is a retrospective, dual-center observa-tional study implementing patients that underwent major thoracic surgery including lung trans-plantation and received concurrent placement of thoracic epidural catheters for postoperative an-algesia. An electronic system of referral and documentation of complications was used, and information was retrieved from our electronic critical care charting system. Side effects such as nausea and vomiting , itching, catheter related issues and also major complications such as epidural haematoma, abscess, or permanent nerve damage were investigated.
The study aims to highlight the importance of a solid documentation and recording system alongside with the implementation of safety protocols.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 20 Years 至 80 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All patients undergoing major thoracic surgery ASA1-3
- •All patients undergoing lung transplantation
排除标准
- •Active bleeding
- •Coagulopathy
- •High inflammatory markers
- •Lack of patients' consent for throracic epidural insertion
结局指标
主要结局
incidence of major complications
时间窗: 3 YEARS
次要结局
未报告次要终点
研究者
DESPOINA SARRIDOU
Assistant Professor of Anaesthesia
AHEPA University Hospital
