Consequences of Using Thoracic Epidural Analgesia for Coronary Artery Bypass Grafting
Overview
- Phase
- Early Phase 1
- Intervention
- CABG
- Conditions
- Coronary Artery Occlusion
- Sponsor
- Volgograd State Medical University
- Enrollment
- 300
- Locations
- 1
- Primary Endpoint
- hospital mortality
- Last Updated
- 4 years ago
Overview
Brief Summary
Investigators plan to study the effect of thoracic epidural analgesia on postoperative parameters (complication rate, duration of hospitalization, mortality, etc.) of coronary artery bypass grafting.
Detailed Description
Investigators plan to conduct a comparative analysis of early postoperative complications of coronary artery bypass grafting with and without cardiopulmonary bypass in patients with independent risk factors for the development of postoperative complications (advanced age, diabetes mellitus, chronic kidney disease, obesity, chronic obstructive pulmonary disease) with various types of anesthesiology benefits (general anesthesia and thoracic epidural analgesia versus general anesthesia and opioids). Investigators predict a decrease in the risk of developing cardiac, respiratory, infectious and renal complications, a reduction in the duration of intensive care, inpatient treatment and mortality.
Investigators
Mikhail I Turovets, MD
professor
Volgograd State Medical University
Eligibility Criteria
Inclusion Criteria
- •coronary artery bypass grafting
Exclusion Criteria
- •Absolute contraindications for the use of thoracic epidural analgesia
Arms & Interventions
Thoracic epidural analgesia
CABG and thoracic epidural analgesia will be used for perioperative analgesia postoperative period
Intervention: CABG
Thoracic epidural analgesia
CABG and thoracic epidural analgesia will be used for perioperative analgesia postoperative period
Intervention: thoracic epidural analgesia
Opioids
CABG and opioids will be used for perioperative analgesia
Intervention: CABG
Opioids
CABG and opioids will be used for perioperative analgesia
Intervention: analgesia of opioids
CABG
coronary artery bypass grafting with and without cardiopulmonary bypass
Intervention: CABG
Outcomes
Primary Outcomes
hospital mortality
Time Frame: 1 year
Duration of treatment in the intensive care unit
Time Frame: up to 1 year
Hospitalization duration
Time Frame: 1 year
Secondary Outcomes
- Complications(1 year)