Consequences of Using Thoracic Epidural Analgesia for Coronary Artery Bypass Grafting
试验速览
- 阶段
- 早期 1 期
- 发起方
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- hospital mortality
研究概览
简要总结
Investigators plan to study the effect of thoracic epidural analgesia on postoperative parameters (complication rate, duration of hospitalization, mortality, etc.) of coronary artery bypass grafting.
详细描述
Investigators plan to conduct a comparative analysis of early postoperative complications of coronary artery bypass grafting with and without cardiopulmonary bypass in patients with independent risk factors for the development of postoperative complications (advanced age, diabetes mellitus, chronic kidney disease, obesity, chronic obstructive pulmonary disease) with various types of anesthesiology benefits (general anesthesia and thoracic epidural analgesia versus general anesthesia and opioids). Investigators predict a decrease in the risk of developing cardiac, respiratory, infectious and renal complications, a reduction in the duration of intensive care, inpatient treatment and mortality.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 90 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •coronary artery bypass grafting
排除标准
- •Absolute contraindications for the use of thoracic epidural analgesia
研究组 & 干预措施
Thoracic epidural analgesia
CABG and thoracic epidural analgesia will be used for perioperative analgesia postoperative period
干预措施: CABG (Procedure)
Thoracic epidural analgesia
CABG and thoracic epidural analgesia will be used for perioperative analgesia postoperative period
干预措施: thoracic epidural analgesia (Drug)
Opioids
CABG and opioids will be used for perioperative analgesia
干预措施: CABG (Procedure)
Opioids
CABG and opioids will be used for perioperative analgesia
干预措施: analgesia of opioids (Drug)
CABG
coronary artery bypass grafting with and without cardiopulmonary bypass
干预措施: CABG (Procedure)
结局指标
主要结局
hospital mortality
时间窗: 1 year
Duration of treatment in the intensive care unit
时间窗: up to 1 year
Hospitalization duration
时间窗: 1 year
次要结局
- Complications(1 year)
研究者
Mikhail I Turovets, MD
professor
Volgograd State Medical University
