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Clinical Trials/NCT06697600
NCT06697600
Recruiting
N/A

A Decisional Intervention for Older Adults With Acute Myeloid Leukemia and Their Caregivers

University of Rochester4 sites in 1 country1,020 target enrollmentJuly 11, 2025

Overview

Phase
N/A
Intervention
Not specified
Conditions
Oncology
Sponsor
University of Rochester
Enrollment
1020
Locations
4
Primary Endpoint
Distress Thermometer Questionnaire at 1 month
Status
Recruiting
Last Updated
4 months ago

Overview

Brief Summary

This is a multicenter randomized controlled trial that assesses the efficacy of a decisional intervention [University of Rochester-Geriatric Oncology assessment for Acute myeloid Leukemia (UR-GOAL)] compared to an attention control.

Detailed Description

This is a multicenter randomized controlled trial with four sites that assesses the efficacy of a decisional intervention \[University of Rochester-Geriatric Oncology assessment for Acute myeloid Leukemia (UR-GOAL)\] compared to an attention control. Subjects will be randomized 1:1 to either the intervention arm or the attention control arm. Compared to an attention control, UR-GOAL will improve patient distress, observed and patient-perceived shared decision making (SDM), and patient decisional conflict.

Registry
clinicaltrials.gov
Start Date
July 11, 2025
End Date
June 1, 2030
Last Updated
4 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Kah Poh Loh

Associate Professor, Division of Hematology/Oncology, Department of Medicine

University of Rochester

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Distress Thermometer Questionnaire at 1 month

Time Frame: 1 month

A self-report measure to capture distress and identify a list of sources of that distress. This is a 10-item scale, rated from 0-10 (0=no distress, 10=severe distress), with a possible total of 10; a higher score indicates greater distress.

Secondary Outcomes

  • 9-item Shared Decision Making Questionnaire at 2 weeks(2 weeks)
  • Decisional Conflict Scale Questionnaire at 2 weeks(2 weeks)
  • Observed shared decision making(Day 0)

Study Sites (4)

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