Efficacy of using scalp cooling caps in prevention of chemotherapy-induced alopecia
Phase 3
Recruiting
- Conditions
- Breast malignancy.Malignant neoplasm of breast
- Registration Number
- IRCT20141102019783N4
- Lead Sponsor
- Vice chancellor for research, Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
consent for using the cap and filling on the questionnaire
using chemotherapy regimens resulting in total alopecia including: 1. Doxorobicin plus cyclophosphamide followed by one of the Taxane drugs (in one, two or three-week regimens) 2. BEP regimen in gonadal malignanciy 3. FEC (5Fu-Epirubicin -cyclophosphamaid) regimen 4. VAC (vincristin-Doxorobicin -cyclophosphamaid) regimen in sarcomas
performance higher than 70%
age between 18 to 75 years
Exclusion Criteria
Melanoma
Blood malignancies
Liver or kidney dysfunction
Migraine
History of cryoglobulinemia
Systemic lupus erythematosus
No consent for using the caps
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Alopecia. Timepoint: prior to each chemotherapy cycle. Method of measurement: visual inspection and questionnaire based on WHO alopecia grading.
- Secondary Outcome Measures
Name Time Method Headache. Timepoint: following every cycle of chemotherapy. Method of measurement: qestionnaire.