PreCoCa - "Prehospital Cooling With Cool-Caps"
Phase 2
Completed
- Conditions
- Heart Arrest
- Registration Number
- NCT00398671
- Lead Sponsor
- Charite University, Berlin, Germany
- Brief Summary
This study shall investigate the feasibility of the use of cool-caps in the preclinical setting in patients with successful primary cardio-pulmonary resuscitation Hypothesis: cool-caps are efficient and feasible to use in the preclinical setting in patients after successful CPR.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
- All patients with primary successful CPR
Exclusion Criteria
- Age < 18
- Pregnancy
- Severe bleeding or severe trauma
- Body core temperature < 34 degrees celsius
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Body core temperature at hospital/ ICU admission 1 day
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What neuroprotective mechanisms underlie prehospital hypothermia using cool-caps in post-cardiac arrest patients?
How does prehospital cool-cap therapy compare to targeted temperature management (TTM) in improving neurological outcomes after cardiac arrest?
Which biomarkers (e.g., serum lactate, inflammatory cytokines) predict response to prehospital hypothermia in NCT00398671 participants?
What adverse events are associated with prehospital cool-cap use, and how do they compare to intravenous cooling methods in cardiac arrest survivors?
Are there combination therapies (e.g., sedatives, anticonvulsants) that enhance neuroprotection when used with prehospital hypothermia in post-CPR care?
Trial Locations
- Locations (1)
Charite University Hospital
🇩🇪Berlin, Germany