Association of Circulating Chemerin Levels and Arterial Stiffness

• Conditions: Obesity; Atherosclerosis

• Registration Number: NCT01293929
• Lead Sponsor: Korea University

Brief Summary

Chemerin is a novel adipokine that might provide a link between chronic inflammation and obesity. Pulse wave velocity(PWV) is a useful method for examining arterial stiffness, meaning early-stage atherosclerosis. Therefore, in the present study, the investigators examined the relationship between circulating chemerin and arterial stiffness measured using PWV in obese persons.

Detailed Description

Not available

Study Timeline

• Status Verified: 2011-01
• Study Start: 2011-02
• Study First Submitted: 2011-02-10
• Study First Submitted QC: 2011-02-10
• Study First Posted: 2011-02-11
• Primary Completion: 2011-03
• Study Completion: 2011-03
• Last Update Submitted: 2011-03-03
• Last Update Posted: 2011-03-04

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• Self referred persons for visiting routine medical check in our clinic

Exclusion Criteria

• Malignancy
• Severe renal or hepatic disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The difference of serum chemerin level between obese and non-obese groups	at the time of initial enrollment (4weeks)	serum chemerin levels of all participants were by determined by an enzyme-linked immunosorbent assay (ELISA) kit (Biovender Laboratory Medicine Inc., Modrice, Czech Republic)

Secondary Outcome Measures

Name	Time	Method
The correlation of serum chemerin levels with arterial stiffness	at the time of enrollment (4 weeks)	Arterial stiffness was measure using a Colin Waveform Analyser (model BP-203RPE II; Colin, Komaki, Japan). It was expressed as branchial ankle pulswe wave velocity (baPWV)

Trial Locations

Locations (1)

Hye Jin Yoo; 🇰🇷 Seoul, Korea, Republic of