Effect of grape seed extract on serum paraoxonase activity in different Paraoxonase Phenotypes
Not Applicable
- Conditions
- hyperlipidemia.Hyperlipidaemia, unspecified
- Registration Number
- IRCT138902073812N2
- Lead Sponsor
- Tabriz University of Medical Science-Drug Applied Research Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
healthy adults with
TG> 150 mg / dl and T.chol> 200mg/dl and had to be willing to cooperate.
Exclusion Criteria
1. Severe hyperlipidemia
2.Treatment by Hyperlipidemic drugs or other drugs (two months before)
3. Consumption of vegetarian diets
4. Alcoholism
5. Kidney or heart failure
6. Malignant disease
7. BMI> 30 kg/m2
8. Chronic liver disease (transaminase two times more than normal)
9. Diabetes
10. Smoking and Tobacco
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ipid profile changes in hyperlipidemic pathients. Timepoint: Before and 8 week after intervention. Method of measurement: Spectrophotometric method.
- Secondary Outcome Measures
Name Time Method Changes in the PON activity. Timepoint: Before and 8 week after intervention. Method of measurement: Spectrophotometric method.