Inactive FSH in Galactosemia
Not Applicable
- Conditions
- GalactosemiaPremature Ovarian Failure
- Interventions
- Registration Number
- NCT00619333
- Lead Sponsor
- Maastricht University Medical Center
- Brief Summary
The aim of the study is to investigate whether inactive FSH plays a role in the development of Premature Ovarian Failure in women with Classic Galactosemia
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 25
Inclusion Criteria
- Diagnosis of galactosemia through GALT-activity analysis and/or mutation analysis
- Premature Ovarian Failure with FSH > 30 U/l
Exclusion Criteria
- Gynecological cancers and/or unexplained vaginal bleeding
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description 1 follitropin and lutropin -
- Primary Outcome Measures
Name Time Method Estradiol response 3 days
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link inactive FSH to ovarian dysfunction in Classic Galactosemia patients?
How does follitropin and lutropin intervention compare to standard hormone therapies for Premature Ovarian Failure in galactosemic women?
Which biomarkers correlate with FSH receptor activity in Classic Galactosemia-associated ovarian failure?
What adverse events are associated with follitropin/lutropin treatment in metabolic disorders like Galactosemia?
Are there combination therapies involving FSH agonists that improve ovarian function in Classic Galactosemia patients?
Trial Locations
- Locations (1)
Maastricht University Hospital
🇳🇱Maastricht, Netherlands
Maastricht University Hospital🇳🇱Maastricht, Netherlands