Study of Follicle Stimulating Hormone (FSH) Receptor in Women With Low Antral Follicle Count

Completed

• Conditions: Fertility; Antral Follicle Deficit

• Registration Number: NCT00231504
• Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Brief Summary

The deficit in the total number of antral follicles is associated with a reduction of the ovarian fertility potential in young women.

The principal objective of this study is to evaluate the relationship between FSH receptor polymorphism and antral follicle count.

The investigators have designed a study of FSH receptor polymorphisms P1 and P2 as an association with a low antral follicle count in the ovary.

Detailed Description

The present study will compare the prevalence of FSH receptor polymorphisms P1 and P2 in women having reduced follicle count (1 to 9 antral follicles) or normal follicle count (13 to 20 antral follicles) determined by ultrasound scans.

Study Timeline

• Study Start: 2005-10
• Study First Submitted: 2005-10-03
• Study First Submitted QC: 2005-10-03
• Study First Posted: 2005-10-04
• Status Verified: 2007-03
• Primary Completion: 2009-03
• Study Completion: 2009-05
• Last Update Submitted: 2010-01-05
• Last Update Posted: 2010-01-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 82

Inclusion Criteria

• 18 to 35 years old
• 1 to 9 or 13 to 20 antral follicles
• Caucasian, occidental Europe
• Presence of both ovaries
• Informed consent

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Exclusion Criteria

• Ovarian anomalies
• Menopause
• Pregnancy
• Other diseases

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Antoine Beclere Hospital, Obstetrics and Gynaecology and Reproduction Medicine Service; 🇫🇷 Paris, France