Platelet-Rich and Concentrated Platelet-Poor Plasma to Reduce Air Leak Post-Lobectomy: A Randomized Controlled Trial

Not Applicable

Completed

• Conditions: Lung Cancer

• Registration Number: NCT00665912
• Lead Sponsor: Zimmer Biomet

Brief Summary

The purpose of this study is to determine whether the use of platelet-rich plasma (PRP) and concentrated platelet-poor plasma (PPPc) can reduce the duration of post-operative air leak after lobectomy for lung tumours.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-01
• Study First Submitted: 2008-04-21
• Study First Submitted QC: 2008-04-22
• Study First Posted: 2008-04-24
• Primary Completion: 2010-05
• Study Completion: 2010-11
• Status Verified: 2017-03
• Last Update Submitted: 2017-03-10
• Last Update Posted: 2017-03-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 204

Inclusion Criteria

• Patients requiring a lobectomy

Exclusion Criteria

• Pneumonectomy
• Sleeve lobectomy
• Determination of unresectability (prior to the initiation of lobectomy)
• Wedge resection alone

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Duration of postoperative air leak	Every 4 hours of postop hospital stay, between 4-6 weeks postop

Secondary Outcome Measures

Name	Time	Method
Incidence of air leak, Prolonged air leak (> days), Complications	Every 4 hours of postop hospital stay, between 4-6 weeks postop

Trial Locations

Locations (1)

University of Western Ontario: Division of Thoracic Surgery; 🇨🇦 London, Ontario, Canada