Platelet-Rich and Concentrated Platelet-Poor Plasma to Reduce Air Leak Post-Lobectomy: A Randomized Controlled Trial
Not Applicable
Completed
- Conditions
- Lung Cancer
- Interventions
- Procedure: Standard post-lobectomy wound care plus use of PRP and PPPc prepared by GPS and Plasmax respectivelyProcedure: Standard post-lobectomy wound care
- Registration Number
- NCT00665912
- Lead Sponsor
- Zimmer Biomet
- Brief Summary
The purpose of this study is to determine whether the use of platelet-rich plasma (PRP) and concentrated platelet-poor plasma (PPPc) can reduce the duration of post-operative air leak after lobectomy for lung tumours.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 204
Inclusion Criteria
- Patients requiring a lobectomy
Exclusion Criteria
- Pneumonectomy
- Sleeve lobectomy
- Determination of unresectability (prior to the initiation of lobectomy)
- Wedge resection alone
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 1 Standard post-lobectomy wound care plus use of PRP and PPPc prepared by GPS and Plasmax respectively Standard post-lobectomy wound care plus use of PRP and PPPc in the thoracic cavity. 2 Standard post-lobectomy wound care Standard post-lobectomy wound care in the thoracic cavity
- Primary Outcome Measures
Name Time Method Duration of postoperative air leak Every 4 hours of postop hospital stay, between 4-6 weeks postop
- Secondary Outcome Measures
Name Time Method Incidence of air leak, Prolonged air leak (> days), Complications Every 4 hours of postop hospital stay, between 4-6 weeks postop
Trial Locations
- Locations (1)
University of Western Ontario: Division of Thoracic Surgery
🇨🇦London, Ontario, Canada