EUCTR2006-003795-35-NL进行中（未招募）不适用
Mannitol inhalations as a faster procedure for testing of airways hyperresponsiveness - Mannitol en AHR
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 120
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Asthmatics:
- •-Episodic symptoms of dyspnea, and/or wheezing, and/or cough
- •-Allergic or non-allergic
- •-PC20 MCh < 8 mg/ml
- •COPD patients:
- •-Age > 40 yrs
- •-Active or former smokers, with a smoking history of more than 10 packyears
- •-Continuous symptoms of cough/sputum and/or dyspnea on exertion
- •-No history of asthma
- •-FEV1/FVC < 70 % and FEV1 < 80 %pred.
- •Subjects without hyperresponsiveness:
- •-No history of asthma or COPD
- •-PC20 methacholine > 8 mg/mL.
- •-FEV1/FVC > 70 % and FEV1 > 80 %pred
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •-Age <18 years
- •-Inability to perform acceptable-quality spirometry or to understand directions given by personnel
- •-Severe airflow limitation (FEV1 < 50% of predicted or < 1.0 L)
- •-Heart attack or stroke in last 3 months
- •-Uncontrolled hypertension, systolic BP > 200, or diastolic BP > 100
- •-Known aortic aneurysm
- •-Pregnancy
- •-Nursing mothers
- •-Current use of cholinesterase inhibitor medication (for myasthenia gravis)
研究者
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Mannitol inhalations as faster procedure for testing of airways hyperresponsiveness.NL-OMON21125Department of Respiratory MedicineUniversity Medical Center GroningenPostbox 30.0019700RB Groningenthe Netherlands120
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