Clinical Study of Fangji Huangqi Decoction in Treating Chronic Heart Failure
- Conditions
- Heart failure
- Registration Number
- ITMCTR2100005429
- Lead Sponsor
- The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
(1) Meet the diagnostic criteria of chronic heart failure in western medicine;
(2) Comply with the syndrome differentiation standard of chronic heart failure with Qi deficiency and blood stasis combined with water in-drinking stop syndrome;
(3) LVEF<50% and NT-proBNP>450ng/l;
(4) NYHA classification of heart function is ?~?;
(5) There is no restriction on gender;
(6) 18 years old = age = 85 years old;
(7) Sign the informed consent form.
(1) Patients with acute coronary syndrome, acute myocardial infarction within 6 months, patients with revascularization within 6 months, or patients with planned revascularization within 1 week, cardiogenic shock, fatal arrhythmia, Cardiomyopathy, rheumatic heart valve disease, myocarditis, constrictive pericarditis, pulmonary embolism, etc.;
(2) Patients with severe liver and kidney dysfunction [ALT and or AST> 3 times the upper limit of the normal reference value; GFR <30ml/(min·1.73m2)];
(3) Combined with serious primary diseases such as endocrine system and hematopoietic system;
(4) Women who are planning to give birth, pregnancy or lactation in the past 3 months;
(5) Mental patients;
(6) People with allergies, or those who are known to be allergic to this medicine and its ingredients;
(7) Those who have participated in other clinical trials within the past 3 months.
(8) The investigator judges that the survival period does not exceed 3 months;
(9) The investigator judged that he could not complete the study or could not comply with the requirements of the study.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method KCCQ;
- Secondary Outcome Measures
Name Time Method T-proBNP;Heart function classification (NYHA);Echocardiogram;6MWD;