Is intramuscular progesterone as effective as oral nifedipine for treating threatened preterm labor?
Not Applicable
- Conditions
- Preterm Labor.Preterm labour without delivery
- Registration Number
- IRCT201112198469N1
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 80
Inclusion Criteria
Women aged 18-45 years; women with single pregnancy; women with pregnancy between 26-34 weeks of gestational age; women who referred with active uterine contractions and admitted for threatened preterm labor.
Exclusion criteria:
women with active labor phase (Cervical dilatation>3cm; vaginal bleeding; rapture of membrane; over distension of the uterus (multifetal gestation or polihydramnios); any systemic infection; oral temperature>38; intrauterine growth retard (IUGR) fetus; fetal distress; blood pressure>140/90 mmHg; any contraindication for progestrone or nifedipine administration; history of any thromboembolic disorders.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Stopping uterine contractions. Timepoint: Before intervention, each hour until contractions stop, 12 hours after stopping contractions. Method of measurement: Tocometry.
- Secondary Outcome Measures
Name Time Method Delivery time. Timepoint: Date of neonate's birth. Method of measurement: Gestational age at the time of delivery.;Reccurance of preterm contractions. Timepoint: every week. Method of measurement: tocometry.;Neonate status. Timepoint: Time of delivery, time of discharge. Method of measurement: Apgar score, hospitalization period, need for NICU.