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Predictors for Recurrence of Atrial Fibrillation After Electrical Cardioversion

Conditions
Atrial Fibrillation
Registration Number
NCT03346863
Lead Sponsor
Vestre Viken Hospital Trust
Brief Summary

In patients with persistent atrial fibrillation (AF), electrical cardioversion is very effective in restoring sinus rhythm if modern, biphasic cardioverters are used. However, approximately 50 per cent of the successfully cardioverted patients experience a recurrence of AF within a few weeks. Therefore, valid predictors for AF recurrence would be of great clinical relevance, to avoid unnecessary procedures.

In the PRE-ELECTRIC study, we will investigate the predictive value of potential new biomarkers with respect to AF recurrence within 30 days after electrical cardioversion. We will investigate serum and plasma biomarkers, electrocardiological markers and echocardiographic variables in this respect. The study will be undertaken as a prospective cohort study at Bærum Hospital, Vestre Viken Hospital Trust, with national and international collaborators.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
270
Inclusion Criteria
  • Patients > 18 years referred for electrical cardioversion for persistent atrial fibrillation
  • Signed, informed consent
Exclusion Criteria
  • Patients < 18 years
  • Patients with paroxysmal atrial fibrillation
  • Patients unwilling to participate or without consent competence

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Atrial fibrillation recurrence30 days after electrical cardioversion

ECG-documented atrial fibrillation recurrence after successful cardioversion

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Bærum Hospital, Vestre Viken

🇳🇴

Sandvika, Bærum, Norway

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