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FGF21 and Fructose Challenge in Humans

Not Applicable
Completed
Conditions
Fasting
Registration Number
NCT02884791
Lead Sponsor
Beth Israel Deaconess Medical Center
Brief Summary

The primary aim of this study is to examine the effect of acute ingestion of fructose on serum FGF21 levels. Subjects in this study will be lean volunteers and individuals with metabolic syndrome.

Detailed Description

Participation in this study involves fasting overnight, drinking a sweet beverage, and several blood draws through an IV line. Each subject may drink up to 10 different sweet beverages, separated by 2 weeks.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
50
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Change in Fibroblast Growth Factor 21 levels in human serum5 hours
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Beth Israel Deaconess Medical Center

🇺🇸

Boston, Massachusetts, United States

Beth Israel Deaconess Medical Center
🇺🇸Boston, Massachusetts, United States

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