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Clinical Trials/NCT02506205
NCT02506205
Unknown
Not Applicable

The Effect of LSVT LOUD for Mandarin-speaking Individuals With Hypokinetic Dysarthria Due to Parkinson's Disease

National Taiwan University Hospital1 site in 1 country40 target enrollmentOctober 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Hypokinetic Dysathria
Sponsor
National Taiwan University Hospital
Enrollment
40
Locations
1
Primary Endpoint
Speech intelligibility
Last Updated
10 years ago

Overview

Brief Summary

A handful of studies have examined the effects of the Lee Silverman Voice Treatment (LSVT) LOUD on hypokinetic dysarthria in English speakers with Parkinson's disease (PD). Although LSVT LOUD has been found to be effective on improving these speaker's vocal intensity and increasing their speech intelligibility as well as speech function with Phase I evidence, no study has investigated whether Mandarin-speaking individuals with dysarthria secondary to PD would benefit from LSVT LOUD. In the proposed study, speech data of Mandarin-speaking individuals with hypokinetic dysarthria before and after speech therapy will be audio recorded and analyzed in order to examine the effects of LSVT LOUD on the speech function in this population. The same speech data will be played to Mandarin listeners in order to investigate the speech intelligibility of this population. It is hypothesized that Mandarin-speaking individuals with hypokinetic dysarthria secondary to PD will demonstrate reduced vocal intensity, reduced speech intelligibility and impaired speech function before they receive LSVT LOUD. They will improve these speech characteristics following speech therapy and will present with short-term maintenance effects.

Registry
clinicaltrials.gov
Start Date
October 2014
End Date
December 2015
Last Updated
10 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

National Taiwan University Hospital

National Taiwan University Hospital

National Taiwan University Hospital

Eligibility Criteria

Inclusion Criteria

  • Mandarin-speaking Taiwanese
  • Hypokinetic dysarthria due to Parkinson's disease
  • No other neurodegenerative diseases
  • No cognitive deficits
  • Age range 30 years and above

Exclusion Criteria

  • Not able to follow verbal directions,
  • speech characteristics uncommon to Parkinson's disease

Outcomes

Primary Outcomes

Speech intelligibility

Time Frame: Immediate

Speech intelligibility will be assessed by native Mandarin listeners' orthographic transcription accuracy and ratings based on a nine-point Likert scale (from 1 - very difficult to understand to 9 - very easy to understand).

Secondary Outcomes

  • Speech function(Immdediate)

Study Sites (1)

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