Enhancing Cognitive Abilities With Comprehensive Training

Not Applicable

Completed

• Conditions: Cognitive Abilities

• Registration Number: NCT02367898
• Lead Sponsor: Lumos Labs, Inc.

Brief Summary

The purpose of this study is to measure the efficacy of an online cognitive training program against an active control condition in a large, randomized trial.

Detailed Description

The present study aims to evaluate a targeted, progressively challenging, online cognitive training program comprised of 49 distinct exercises targeting a variety of cognitive capacities. The cognitive training program will be compared to a plausibly beneficial active control condition in which participants completed online crossword puzzles.

The investigators hypothesize that the cognitive training will show greater transfer to a range of underlying cognitive abilities than the active control, as measured by a broad battery of neuropsychological assessments and participant-reported outcomes.

Study Timeline

• Study Start: 2013-04
• Primary Completion: 2014-04
• Study Completion: 2014-04
• Study First Submitted: 2015-02-13
• Study First Submitted QC: 2015-02-19
• Study First Posted: 2015-02-20
• Status Verified: 2015-09
• Last Update Submitted: 2015-09-09
• Last Update Posted: 2015-09-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 11470

Inclusion Criteria

• Engaged with the Lumosity program at least 3 days in the first week after sign-up
• Access to an internet enabled computer to complete training

Exclusion Criteria

• Paying subscriber

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Aggregate Cognitive Performance	Baseline to 10 weeks	Aggregate cognitive performance, as measured by Grand Index, on seven neuropsychological assessments (Forward Memory Span, Reverse Memory Span, Grammatical Reasoning, Progressive Matrices, Go/No-Go, Arithmetic Reasoning, Two-Target Search)

Secondary Outcome Measures

Name	Time	Method
Participant-Reported Outcomes	Baseline to 10 weeks	9 questions related to everyday cognition and emotional status.
Individual Neuropsychological Assessments composite	Baseline to 10 weeks	Separate analyses of changes on each of the seven neuropsychological assessments in the battery (Forward Memory Span, Reverse Memory Span, Grammatical Reasoning, Progressive Matrices, Go/No-Go, Arithmetic Reasoning, Two-Target Search).

Trial Locations

Locations (1)

Lumos Labs, Inc.; 🇺🇸 San Francisco, California, United States