KCT0002686
Recruiting
未知
Therapeutic Efficacy of Autologous Platelet Concentrate on Macular hole with High myopia, Large Macular Hole or Recurrent Macular Hole ; Randomized clinical trial
ational Evidence-based Healthcare Callaborating Agency0 sites194 target enrollmentTBD
ConditionsDiseases of the eye and adnexa
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Diseases of the eye and adnexa
- Sponsor
- ational Evidence-based Healthcare Callaborating Agency
- Enrollment
- 194
- Status
- Recruiting
- Last Updated
- 7 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients who were diagnosed as full\-thickness macular hole by optical coherence tomography with visual acuity of affected eye under 20/50 were included. All subject had to meet at least one of the following conditions.
- •1\) macular hole over 400µmof minimum size
- •2\) macular hole at high myopic eye (spherical equivalent over \-6\.0 diopters, or axial length over 25\.5 millimeters)
- •3\) relapsed of recurrent macular hole
Exclusion Criteria
- •Patients with any following condition were excluded.
- •1\. Pregnancy
- •2\. History of retinal detachment, or proliferative vitreoretinopathy in affected eye
- •3\. History of vitreoretinal surgery for the ocular disease other than macular hole
- •4\. Proliferative diabetic retinopathy, vitreous hemorrhage, retinal vascular obstruction, uveitis, trauma, optic nerve atrophy, intraocular tumor, or visually significant corneal opacity in affected eye
- •5\. Confirmed or suspicious intraocular/periocular infection
- •6\. Uncontrolled high Intraocular pressure (over 21 mmHg) with maximal tolerant medical treatment, or history of glaucoma surgery
- •7\. Contraindications for using autologous platelet concentrate (thrombocytopenia,any type of thromboasthenia, positive serology of hepatitis B, C, or human immunodeficiency virus, positive serology of syphilis)
- •8\. Hemodynamic instability
- •9\. Septicemia
Outcomes
Primary Outcomes
Not specified
Similar Trials
Recruiting
Phase 3
Efficacy of autologous platelet-rich plasma and laser acupuncture in the treatment of non-obstructive azoospermiaIRCT20111121008146N43Shahid Beheshti University of Medical Sciences30
Active, not recruiting
Phase 1
Efficacy of plasma injections, and extracorporeal shock wave therapy, in thetreatment of work –related lateral epicondylitisThe epicondylitis is an overuse injury, in most cases, is a self-limited course andresponds well to conservative treatment. Its etiology is degenerative and is relatedto a repetitive overuse and underlying tendinopathy.Therapeutic area: Diseases [C] - Musculoskeletal Diseases [C05]EUCTR2018-002650-67-ESIbermutuamur (Mutua Colaboradora con la Seguridad Social nº 274)66
Active, not recruiting
Phase 1
Check the efficacy of PRP in vascular ulcers in primary care.EUCTR2014-001514-26-ESComarca Ezkerraldea-Enkarterri (OSAKIDETZA)150
Recruiting
Not Applicable
Assessment the effect of using autologous platelet rich plasma (PRP) in prevention of hypertrophic scarIRCT20201007048955N2Clinical Research Development Center50
Not yet recruiting
Not Applicable
Clinical and radiographic comparison of extraction socket healing of mandibular third molars following the use of autologous platelet-rich plasma and fibrin :randomized controlled trial.bony defectOral and Gastrointestinal - Normal oral and gastrointestinal development and functionACTRN12624001146583Ufaq rao ,shifa dental hospital12