To Study Correlation Of Two Blood Gas Analysis Derived Parameters, Veno-Arterial Carbon Dioxide Pressure Difference To Arterio-Venous Oxygen Content Difference Ratio With Lactate Clearance Rate During Early Resuscitation In Septic Shock Patients

Not yet recruiting

• Conditions: Sequelae of other specified infectious and parasitic diseases. Ayurveda Condition: AUPASARGIKA-TRUSHNA,

• Registration Number: CTRI/2021/02/031158
• Lead Sponsor: ABVIMS DR RAM MANOHAR LOHIA HOSPITAL

Brief Summary

This is Prospective Observational Cohort Study to be carried out to find correlation of Veno-arterial carbon dioxide pressure difference to Arterio-venous content difference ratio with lactate clearance rate for early resuscitation goal in septic shock patients admitted for more than 24 hrs in mixed surgical & medicine ICU in 55 patients of age more than 18 yrs of either sex.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-11-02

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 55

Inclusion Criteria

18 yrs Admitted in ICU for more than 24 hrs for both medical or surgical disease with septic shock.

Exclusion Criteria

1 Refusal of Consent 2 Drop out during sampling period 3 Pregnant females 4 Liver Cirrhosis child Pugh C 5 End stage renal disease 6 Sustained hemodynamic unstable Cardiac arrhythmias or LVEF < 35% 7 Severe COPD (grade 3&4).

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. To determine correlation between Veno-arterial carbon dioxide pressure difference to arterio-venous oxygen content difference (Pcv-aCo2/Ca-cvO2) ratio and lactate clearance	24 hrs
rate (T24) for early resuscitation goal in septic shock patients	24 hrs

Secondary Outcome Measures

Name	Time	Method
1. To determine Correlation between Pcv-aCo2/Ca-cvO2 ratios (T24) with lactate	levels, Scvo2, Pv-aCo2 clearance

Trial Locations

Locations (1)

DR SEEMA BALKRISHNA WASNIK; 🇮🇳 Central, DELHI, India

DR SEEMA BALKRISHNA WASNIK

🇮🇳Central, DELHI, India

DR SEEMA BALKRISHNA WASNIK

Principal investigator

01123404699

wasnikseema@gmail.com