A Randomized Clinical Trial of Oral Health Promotion Interventions Among Patients Following Stroke
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Acute Stroke
- Sponsor
- The University of Hong Kong
- Enrollment
- 102
- Locations
- 1
- Primary Endpoint
- Change in plaque scores over course of trial
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
The main aim of this oral health intervention project is to compare the effect of providing 1) professional oral hygiene instruction alone versus 2) professional oral hygiene instruction plus adjunctive Chlorhexidine mouth rinse versus 3) professional oral hygiene instruction plus adjunctive assisted tooth brushing and Chlorhexidine mouth rinse, on the oral health condition, the general health condition and health-related quality of life (HRQoL) of patients with stroke who are receiving hospital-based rehabilitation. An additional aim is to assess potential longer term oral intervention-related health and HRQoL outcomes.
Investigators
Dr. Otto Lok-Tao Lam
Clinical assistant professor
The University of Hong Kong
Eligibility Criteria
Inclusion Criteria
- •Aged 50 years and over
- •Moderate to severe stroke (Barthel Index \>/= 70)
- •Admitted to Rehabilitation Unit within 7 days
Exclusion Criteria
- •Patients with naso-gastric feeding tube
- •Edentulous patients
- •Patients with communication difficulties
Outcomes
Primary Outcomes
Change in plaque scores over course of trial
Time Frame: Three week in-hospital rehabilitation period
Secondary Outcomes
- Change in oral health-related quality of life over course of trial(Three week in-hospital rehabilitation period)
- Change in gingival bleeding scores over course of trial(three week in-hospital rehabilitation period)
- Change in oral colonization by Staphylococcus aureus over course of trial(Three week in-hospital rehabilitation period)
- Change in oral colonization by yeasts over course of trial(Three week in-hospital rehabilitation period)
- Change in oral colonization by aerobic and facultatively anaerobic Gram-negative bacilli over course of trial(Three week in-hospital rehabilitation period)
- Change in health-related quality of life over course of trial(three week in-hospital rehabilitation period)