Changes of Regional Tissue Oxygenation Saturation After Successful Femoral Nerve Block
- Conditions
- Anesthesia, Local
- Registration Number
- NCT03753594
- Lead Sponsor
- Huazhong University of Science and Technology
- Brief Summary
Regional tissue oxygenation saturation has been shown to increase in innervated regions after sympathetic block. The aim of this prospective observational study was to evaluate the changes of regional tissue oxygenation saturation by near-infrared spectroscopy after successful femoral nerve block with ropivacaine and determine whether the changes of regional tissue oxygenation saturation can be affected by the concentration of ropivacaine.
- Detailed Description
Successful peripheral nerve blocks induce sympathetic blockade, which increases local blood flow by vasodilation. The relationship between successful femoral nerve block and the variation of regional tissue oxygenation saturation was unclear.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 100
- Informed consent
- American Society of Anesthesiologists physical statusⅠ-Ⅱ
- Undergo elective elective knee arthroscopy with peripheral nerve block
- Refusal to participate in the study
- BMI>35
- Any contraindications to peripheral nerve block such as coagulation abnormalities, •Allergy to local anaesthetics, peripheral neuropathy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Regional tissue oxygenation saturation after successful femoral nerve block at 5-minute intervals till 30 minutes after regional block rSO2
- Secondary Outcome Measures
Name Time Method Pinprick sensory scores 5 minute before regional block and at 5-minute intervals till 30 minutes after regional block A 3-level scale was used to grade the intensity of sensory block using pinprick stimulation: 0=normal sensation; 1=analgesia; 2=anesthesia.
Trial Locations
- Locations (1)
Union Hospital
🇨🇳Wuhan, Hubei, China
Union Hospital🇨🇳Wuhan, Hubei, China