跳至主要内容
临床试验/NCT01532713
NCT01532713已完成不适用

The Effect of Oxygen Administration on Regional Cerebral Oxygen Saturation (rSO2) in the Non-block Side After Stellate Ganglion Block

Yonsei University2 个研究点 分布在 1 个国家目标入组 38 人开始时间: 2012年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
38
试验地点
2
主要终点
increase on the regional cerebral oxygen saturation

研究概览

简要总结

Stellate ganglion block (SGB) is known to increase blood flow to the innervation area of the stellate ganglion. Near infrared spectroscopy reflects changes of blood volume and allows continuous, non-invasive, and bedside monitoring of regional cerebral oxygen saturation (rSO2). Previous studies have shown the increment of the rSO2 on the block side from the baseline and the decrement of the rSO2 on the non-block side after SGB. Patients with cerebral vascular disease undergoing SGB might be at risk a decrease in cerebral blood flow in the non-block side. The investigators researched the effect of oxygen administration on rSO2 in the non-block side using a near infrared spectroscopy after SGB. 5 L/min oxygen was supplied via nasal cannula from 15 minutes after SGB. The rSO2 in the non-block side were measured before SGB and 5, 10, 15, 20, 25 and 30 minutes after SGB.

The present study suggests that oxygen administration can increase the rSO2 of non-block side. In conclusion, it is our belief that oxygen supplement is helpful to the patient with cerebral vascular disease during SGB.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Prevention
盲法
None

入排标准

年龄范围
20 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • ages between 20 and 70 years
  • ASA PS 1,2
  • disease entity : pain in the head, neck, upper extremity, and SSNHL ( sudden sensory neural hearing loss )

排除标准

  • patient with the tendency to bleed
  • patient who had cerebrovascular disease
  • patient with respiratory disease ( COPD: chronic obstructive lung disease )
  • patients who do not give written informed consent to participate in the study

结局指标

主要结局

increase on the regional cerebral oxygen saturation

时间窗: 5 minutes after oxygen administration

The rSO2 on the non-block side after SGB and additional oxygen administration will be compared with the baseline rSO2.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

Loading locations...

相似试验

The Effect of Oxygen Administration on Regional... | 临床试验