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Therapeutic Effects of Insoles on Patients With Knee Osteoarthritis

Phase 3
Conditions
Knee Osteoarthritis
Interventions
Other: customized insoles
Other: ready made insoles
Registration Number
NCT01765101
Lead Sponsor
Taipei Medical University
Brief Summary

Using double blind, randomized controlled design to study the immediate, short-term and intermediate-term therapeutic effects of ready-made full-length lateral wedged shoe insoles and customized full-length lateral wedged shoe insoles to patients with knee osteoarthritis, under the basis of International Classification Functioning, Disability and Health.

Detailed Description

A total of 90 patients will be collected. The participants will be randomized into two groups, including ready-made full-length lateral wedged shoe insoles group and customized full-length lateral wedged shoe insoles group. The psychological function (Hospital anxiety and depression scale, Graded chronic pain scale, Multidimensional fatigue inventory, Fear-avoidance belief questionnaire), physical activity (CHAMPS physical activity questionnaire), functional performance (Western Ontario and McMaster Universities Osteoarthritis index、Knee injury and Osteoarthritis Outcome Score) and quality of life (World Health Organization-Quality of life-Brief Vision、Osteoarthritis Quality of Life、Osteoarthritis- Knee and Hip Quality of Life) will be evaluated. Physical functional ability (10 meter normal and fast walk, up and down stairs, and 5 repeated chair-rising time), pain (Visual analog scale, pain pressure threshold ) and balance performance (static postural stability and dynamic stability by Biodex Stability System, including postural stability, dynamic limits of stability and fall risk) will be evaluated before and immediately after the ready-made full-length shoe insoles and customized full-length shoe insoles are prescribed. All the evaluations, including physical functional ability, pain, balance, psychological, physical activity, functional performance, and quality of life, will be re-evaluated at one month after and three months after modified shoe insoles wearing. Subjects and evaluator were both blinded to the group's classification during the whole course of study.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
90
Inclusion Criteria
  • fulfill the combined clinical and radiographic criteria for knee osteoarthritis, as established by the American College of Rheumatology
  • with Kellgren-Lawrence scores of 2 or higher in the isolated medial compartment
Exclusion Criteria
  • with a history of previous knee surgery with an implant
  • reduced lateral compartment and/or combined medial and lateral compartments in knee joints were excluded
  • pregnant or planning to become pregnant
  • self-reported history of vertigo, malignancy, stroke, or other conditions that may impair vestibular function

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
customized insolescustomized insolescustomized full-length lateral wedged shoe insoles 1 month and 3 months study the immediate, short-term and intermediate-term therapeutic effects
ready made insolesready made insolesready-made full-length lateral wedged shoe insoles at 1 and 3 months study the immediate, short-term and intermediate-term therapeutic effects
Primary Outcome Measures
NameTimeMethod
painchange from baseline at one month and three months after modified shoe insoles wearing

Visual analog scale, pain pressure threshold

Secondary Outcome Measures
NameTimeMethod
Physical functional abilitychange from baseline at one month and three months after modified shoe insoles wearing

10 meter normal and fast walk, up and down stairs, and 5 repeated chair-rising time

psychological functionchange from baseline at one month and three months after modified shoe insoles wearing

Hospital anxiety and depression scale, Graded chronic pain scale, Multidimensional fatigue inventory, Fear-avoidance belief questionnaire

functional performancechange from baseline at one month and three months after modified shoe insoles wearing

Western Ontario and McMaster Universities Osteoarthritis index、Knee injury and Osteoarthritis Outcome Score

quality of lifechange from baseline at one month and three months after modified shoe insoles wearing

World Health Organization-Quality of life-Brief Vision、Osteoarthritis Quality of Life、Osteoarthritis- Knee and Hip Quality of Life

balance performancechange from baseline at one month and three months after modified shoe insoles wearing

static postural stability and dynamic stability by Biodex Stability System, including postural stability, dynamic limits of stability and fall risk

physical activitychange from baseline at one month and three months after modified shoe insoles wearing

CHAMPS physical activity questionnaire

Trial Locations

Locations (1)

Shin Kong Wu Ho-Su Memorial Hospital

🇨🇳

Taipei, Taiwan

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