A Study to asses the effectiveness of platelet rich plasma injection by intra-articular or rotator interval methods for management of periarthritis shoulder

Not yet recruiting

Conditions: Pain in joint,

Registration Number: CTRI/2021/03/032450

Lead Sponsor: Lady Hardinge Medical College

Brief Summary: Shoulder pain is the 3rd leading cause of musculoskeletal pain after backpain and neck pain. Peri arthritis (PA), adhesive capsulitis, Rotator Cuff Tendinopathy (RCT), Acromioclavicular joint arthritis, Glenohumeral Osteoarthritis, inflammatory arthritis are some of the common causes of shoulder pain. Periarthritis shoulder/Frozen shoulder is a common condition resulting in insidious onset pain and global restriction of motion at the shoulder joint. Peak incidence between 46 and 64 years of age, with females more often affected.There is inflammation, thickening and contracture of the joint capsule as well as soft tissue fibrosis and inflammation of the rotator interval, capsule and ligaments. Painful stiffness of the shoulder can adversely affect activities of daily living and consequently impair quality of life.The typical natural history is of gradual resolution of symptoms over 1 to 3 year period and between 20% to 50% of patients may go on to develop long-lasting symptoms. A plethora of treatment options have been recommended which include benign neglect, oral corticosteroids, intra articular injection of corticosteroids, hyalouronic acid and platelet rich plasma(PRP), physical therapy exercises, deep heat modalities, manipulation under anaesthesia, hydro dilation, arthroscopic release. PRP has emerged as a new technology which is believed to stimulate revascularisation of soft tissue and increase the concentration of growth factors to improve and accelerate tendon healing.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 66

Inclusion Criteria

1.Adults(>18years) with chronic shoulder pain for > 6 months 2.Average Numerical Pain Rating Scale (NRS) > 4.

Exclusion Criteria

1.Any steroid injection within last 8 weeks.
2.Patients having coagulopathies, skin infection over shoulder area and allergy to local anesthetics.
3.Any shoulder surgery or arthroscopy of the affected shoulder within the past one year.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Shoulder Pain and Disability Index (SPADI) at 0,1st and 3rd month in both the groups.	0,1st and 3rd month

Secondary Outcome Measures

Name	Time	Method
1.Mean Numerical Pain Rating Scale(NRS) score at 0,1st and 3rd month follow-up in both the groups.	2.Proportion of patients with Post injection complications (infection or hematoma) at the site of injection in both the therapies.

Trial Locations

Locations (1): Lady Hardinge Medical College
🇮🇳
Central, DELHI, India
Lady Hardinge Medical College
🇮🇳Central, DELHI, India
Dr Shubham Rahul Rai
Principal investigator
9818270302
raishubhamrahul@gmail.com