Influence of an Imaginary Target on the State of Accommodation Under Scotopic Conditions
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 39
- 试验地点
- 2
- 主要终点
- Shift of accommodation in scotopic luminance (Dark focus)
研究概览
简要总结
Shifts in accommodation at decreasing luminance levels are considered as principle cause for night myopia. Previous studies with laser optometers quantified the dark focus of accommodation up to 3 D. In addition to the measurement of dark focus, the aim of this study was to investigate the influence of an imaginary target at finite distances on the state of accommodation at scotopic luminance.
详细描述
Accommodation was measured by using an open-field autorefractor (WAM 5500, GRAND SEIKO). Full corrected right eyes of 39 subjects aged from 18 to 40 years were investigated in this randomized, cross-sectional study. Accommodation measurements in photopic luminance were taken for 6 m of empty field and for optotype fixation at 2 m, 1 m and 0.5 m. At scotopic luminance, dark focus of accommodation was examined directly after darkening and after 10 min of dark adaptation. After adaptation, subjects had to visualize imaginary targets in the four distances while accommodation was measured.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
盲法说明
Sequence of tests was randomized. It is no multi-arm study.
入排标准
- 年龄范围
- 22 Years 至 39 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age 18 - 44
- •visual acuity at least 0.8 (5/6)
排除标准
- •medication with an impact on the visual system
- •visual disease or disease with an impact on the visual system
- •pregnancy or other hormonal variances
- •drug usage
- •overfatigue at the period of investigation
- •mental handicap
研究组 & 干预措施
Accommodation in scotopic luminance
干预措施: Accommodation Measurement (Diagnostic Test)
结局指标
主要结局
Shift of accommodation in scotopic luminance (Dark focus)
时间窗: Baseline only
Accommodative shift in scotopic luminance compared to photopic luminance for empty field (dark focus of accommodation)
次要结局
- Difference of accommodation for 2 m target(Baseline only)
- Difference of accommodation for 1 m target(Baseline only)
- Difference of accommodation for 0.5 m target(Baseline only)
研究者
Philipp Hessler
Principal Investigator
University of Applied Sciences Jena