Effects of exposition to simulated nocturnal railway noise on endothelial function in healthy adults

niversitätsmedizin Mainz, Zentrum für Kardiologie, Kardiologie I0 个研究点目标入组 74 人开始时间: 2017年2月27日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•Physically and mentally healthy adults
•- non-smokers
•- no exposition to nocturnal railway noise at primary place of residence
•-no nighttime noise exposure greater than Leq >45 dB, as determined by municipal noise maps.

•Any regular drug treatment within the last two months, except for oral contraceptives;
•Place of residence with nocturnal road traffic noise Leq> 45 dB;
•Pathologic Pittsburgh-Sleep quality-Index (PSQI) (>10) denoting sleep disorders;
•Evidence of obstructive sleep apnea in screening questionnaire;
•Average daily sleep duration < 6 hours;
•Current shiftwork;
•Sedative use;
•Known epilepsy or other neurological or mental disorder for which sleep restriction is contraindicated;
•Hearing loss > 30 dB audiometry (age adjusted);
•persons actively involved in anti-railway noise groups are excluded as are employees of railway companies or other companies with major financial interest in railway traffic

发起方

niversitätsmedizin Mainz, Zentrum für Kardiologie, Kardiologie I