Treatment trial with Losartan of a patient with stiff skin syndrome.

Completed

• Conditions: congenital scleroderma; stiff skin syndrome; 10028396

• Registration Number: NL-OMON36060
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 1

Inclusion Criteria

Clinical diagnosis of stiff skin syndrome.

Exclusion Criteria

Pregnancy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1. Improvement of joint excursions.<br /><br>2. Improvement of the hardening of the skin.<br /><br>3. Change of fibrosis in the skin.<br /><br>4. Change of the TGF&beta; signaling</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Side effects of Losartan</p><br>